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class="content-box n-box"> <div class="body-right"> <div class="breadCrumb ThemeFborder"> <b>您當前的位置：</b><a href="/">首頁</a><em>></em> <a href="/Article-index.html" class="Themefont">下載</a><em>></em><a href="/Articles-24510.html" class="Themefont">行業資訊</a> </div>   <div class="row"> <div class="news-nr-box"> <style> body .news-nr-box h1{ font-size:18px; font-family:Airal; text-align:center; line-height:25px; padding: 10px 0; margin:0px; color:#333; } </style> <div class="news1-title"> <h1>傳統性別二分法過于簡單</h1> <h6> <span>2015-03-16</span> <span>　來自:  湛江市?？粕锟萍加邢薰? </span> <span style="margin-left:10px;">瀏覽次數:1021</span> </h6> </div> <p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;"><strong style="text-indent: 2em;">性別二分法過于簡單</strong></p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">對DSD開展的研究表明，性別并不是簡單的二分法。當科學家放大來看單個細胞時，事情變得更復雜。認為每個細胞包含相同基因組的常見假設是錯誤的。一些人的身體出現了鑲嵌現象：他們從單個受精卵發育而來，卻成為擁有不同基因組成的細胞的拼湊“作品”。當早期胚胎發育階段中性染色體在分裂細胞間分配不均時，就會發生該現象。例如，最開始擁有XY染色體的胚胎，會從其細胞亞型中失去Y染色體。如果大多數細胞最終擁有XY染色體，就會發育為生理上典型的男性。但如果大部分細胞是X染色體，便會發育成患有被稱為特納氏綜合征的女性，而這往往導致身高受限且卵巢發育不充分。這種鑲嵌現象比較罕見，1.5萬人中約有1人受到影響。</p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">在性染色體鑲嵌現象造成的影響中，曾有病例記錄顯示，擁有XXY染色體鑲嵌的胚胎變成兩種細胞類型的混合，一些擁有兩條X染色體，而另一些擁有兩條X和一條Y染色體，這最終導致不同性別的“同卵”雙胞胎。</p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">還有第二種方式會導致一個人最終擁有從染色體來看是不同性別的細胞。James的病人就是一個嵌合體：從兩個受精卵的混合物發育而來，這通常是由子宮中雙胚胎的合并造成的。這種類型導致的DSD嵌合體極其罕見，在所有DSD病例中約占1%。</p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">不過，另一種形式的嵌合體現在已廣泛存在，即微嵌合體。當來自胚胎的干細胞穿過胎盤進入母體時，微嵌合體便會發生。該現象在上世紀70年代被首次確認出來，但令人大吃一驚的事情是在20多年后才出現。當時，研究人員發現這些穿越細胞能存活很長時間，即便它們是理論上身體應對其進行排斥的外來組織。1996年的一項研究記錄了一些女性在生育后，其血液中的胚胎細胞存活長達27年。另一項研究發現，母體細胞一直在孩子體內存在直到后者成年。這種現象進一步混淆了性別的劃分，因為它意味著男性經常攜帶來自其母親的細胞，而懷有男性嬰兒的女性會攜帶少數該嬰兒的遺棄細胞。</p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">如今，科學家發現擁有XX和XY染色體的細胞表現方式不同，而這不受性激素的影響?！皩嵲拰嵳f，性染色體造成的影響如此之大實在是令人吃驚?！盇rnold表示。他和同事發現，小鼠體內X染色體的多寡會影響其新陳代謝。在實驗室培養皿中開展的研究也表明，擁有XX和XY染色體的細胞在分子水平上表現不同，比如會對壓力作出不同的新陳代謝反應。Arnold介紹說，下一個挑戰是揭示這種機制。</p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;"><strong>性別認同是最合理的指標</strong></p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">生物學家或許一直在建立更加細致入微的性別觀點，但社會并未跟上這種發展。的確，來自同性戀、雙性人和變性人群體成員半個多世紀的激進主義已經使全社會對待性取向和性別的態度有所緩和。不過，當談到性別時，在要求遵從二元模式方面依然存在巨大的社會壓力。</p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">這種壓力意味著，生下來便患有明顯DSD的人經常會遭受使其生殖器正?；耐饪剖中g。這種手術具有爭議性，因為它通常在嬰兒身上進行，而他們又太小，以至于沒法不同意手術。同時，手術還面臨著在分配性別時同孩子最終性別的認同，即他們對自己性別的感知不一致的風險。為此，雙性人聲援團隊認為，醫生和父母至少應等孩子大到能交流自己的性別認同，或者大到能決定是否想要接受手術。</p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">加州大學洛杉磯分?；谛詣e的生物學中心主任Eric Vilain表示，醫生對待性別手術的態度正變得愈發慎重?；加蠨SD的兒童會接受多學科團隊的治療，以便為每位患者及其家庭量身定制管理和支持方法。但這通常涉及將孩子當作男性還是女性撫養，即使不進行外科手術。Vilain說：“將孩子以一種并不存在的性別養大可能很困難?！痹诖蠖鄶祰?，除了成為男性或女性外，其他情況在法律上都是不可能的。</p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">但很多變性人和雙性人激進主義者仍夢想著生活在與一個人的性別不相干的世界中。盡管有些政府正朝該方向努力，但加州圣地亞哥市托馬斯杰斐遜法學院同性別相關的法律問題專家Julie Greenberg對實現該夢想的前景持悲觀態度，至少在美國是這樣?！拔艺J為全部消除性別標記，或者允許第3種模糊的標記將非常困難?！?/p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">因此，如果法律要求一個人必須是男性或女性，那么性別就得根據解剖學特征、激素、細胞或染色體來分配?！拔业母杏X是既然沒有一種生物學指標能超越其他所有指標，最終性別認同似乎是最合理的指標?！盫ilain表示。換句話說，如果你想知道某個人是男性還是女性，或許的方式就是問問那個人</p><p style="margin-top: 10px; margin-bottom: 10px; font-size: 14px; text-indent: 2em; line-height: 25px; overflow: hidden; width: 839.984375px; white-space: normal; background-color: rgb(255, 255, 255); padding: 0px; color: rgb(51, 51, 51); font-family: helvetica, tahoma, arial, 宋體, sans-serif;">作者：中國科學報 </p><p><br/></p> </div> <div class="pager ks-clear"> <span class="iconfont1 iconjiantou newsjiantou-left" style="font-size: 32px!important;display: none;" ></span> <div class="previous fl"> <span style="padding-top: 5px;">上一條：</span> <a title="生物科技股的納斯達克泡沫來了嗎？" class="Themebg Themebghover" href="/Article-detail-id-369866.html">生物科技股的納斯達克泡沫...</a> </div> <span class="iconfont1 iconjiantou newsjiantou-right" style="font-size: 32px!important; display: none;" ></span> <div class="next fr"> <span style="padding-top: 5px; left: none;right: 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